RUDN Journal of Agronomy and Animal IndustriesRUDN Journal of Agronomy and Animal Industries2312-797X2312-7988Peoples’ Friendship University of Russia named after Patrice Lumumba153510.22363/2312-797X-2014-3-49-54Research ArticleThe study of factors affecting the efficiency of somatic transgenesis in chickensPrytkovYu Aprytkov@mail.ruVetokhA NDepartment of standardization, metrology and technology of the livestock products Peoples’ Friendship University of Russia Mikluho-Maklaya str., 8, Moscow, Russia, 117198; Department of standardization, metrology and technology of the livestock products Peoples’ Friendship University of Russia Mikluho-Maklaya str., 8, Moscow, Russia, 117198anastezuya@mail.ruVolkovaN Anatavolkova@inbox.ruNikishovA ADepartment of standardization, metrology and technology of the livestock productsa.nikishov@rudn.ruZinovievaN An_zinovieva@mail.ruAll-Russian State Research Institute of Animal BreedingPeoples’ Friendship University of Russia150320143495405092016Copyright © 2014,2014In this article we studied the impact of the use of retroviral vectors for genetic transformation of chicken oviduct cells in vivo to produce transgenic chickens bioreactors and investigated factors affecting the efficiency of local transgenesis in chickens. By using of retroviral vector system it was shown that with the efficiency of chickens oviduct cells transformation was at least 17,2 ± 3,1%.chickentransgenesisoviductbioreactorsrecombinant DNAкурытрансгенезяйцеводбиореакторырекомбинантная ДНК