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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">RUDN Journal of Agronomy and Animal Industries</journal-id><journal-title-group><journal-title xml:lang="en">RUDN Journal of Agronomy and Animal Industries</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник Российского университета дружбы народов. Серия: Агрономия и животноводство</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2312-797X</issn><issn publication-format="electronic">2312-7988</issn><publisher><publisher-name xml:lang="en">Peoples’ Friendship University of Russia named after Patrice Lumumba</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">19513</article-id><article-id pub-id-type="doi">10.22363/2312-797X-2019-14-3-279-288</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Veterinary science</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Ветеринария</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">LC50 determination and intoxication symptoms of a new pyridine carboxamide pesticide Flonicamid on common carp Cyprinus carpio</article-title><trans-title-group xml:lang="ru"><trans-title>Определение средней летальной концентрации и симптомов интоксикации нового пиридинкарбоксамидного пестицида флоникамида на карпа Cyprinus carpio</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ghelichpour</surname><given-names>Melika</given-names></name><name xml:lang="ru"><surname>Геличпур</surname><given-names>Мелика</given-names></name></name-alternatives><bio xml:lang="en"><p>Department of Aquatic Animal Health, Faculty of Veterinary Medicine</p></bio><bio xml:lang="ru"><p>кафедра здоровья водных животных, факультет ветеринарной медицины</p></bio><email>m.ghelichpour@ut.ac.ir</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Mirghaed</surname><given-names>Ali Taheri</given-names></name><name xml:lang="ru"><surname>Миргаед</surname><given-names>Али Тахери</given-names></name></name-alternatives><bio xml:lang="en"><p>Department of Aquatic Animal Health, Faculty of Veterinary Medicine</p></bio><bio xml:lang="ru"><p>кафедра здоровья водных животных, факультет ветеринарной медицины</p></bio><email>m.ghelichpour@ut.ac.ir</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Jimenez</surname><given-names>Amalia Perez</given-names></name><name xml:lang="ru"><surname>Хименес</surname><given-names>Амалия Перес</given-names></name></name-alternatives><bio xml:lang="en"><p>Department of Zoology</p></bio><bio xml:lang="ru"><p>факультет зоологии</p></bio><email>m.ghelichpour@ut.ac.ir</email><xref ref-type="aff" rid="aff3"/><xref ref-type="aff" rid="aff4"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">University of Tehran</institution></aff><aff><institution xml:lang="ru">Тегеранский университет</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Center for International Scientific Studies &amp; Collaboration (CISSC)</institution></aff><aff><institution xml:lang="ru">Центр международных научных исследований и сотрудничества (CISSC)</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">University of Granada</institution></aff><aff><institution xml:lang="ru">Университет Гранады</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">University of Porto</institution></aff><aff><institution xml:lang="ru">Университет Порту</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2019-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2019</year></pub-date><volume>14</volume><issue>3</issue><issue-title xml:lang="en">VOL 14, NO3 (2019)</issue-title><issue-title xml:lang="ru">ТОМ 14, №3 (2019)</issue-title><fpage>279</fpage><lpage>288</lpage><history><date date-type="received" iso-8601-date="2019-10-03"><day>03</day><month>10</month><year>2019</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2019, Ghelichpour M., Mirghaed A.T., Jimenez A.P.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2019, Геличпур М., Миргаед А.Т., Хименес А.П.</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="en">Ghelichpour M., Mirghaed A.T., Jimenez A.P.</copyright-holder><copyright-holder xml:lang="ru">Геличпур М., Миргаед А.Т., Хименес А.П.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://agrojournal.rudn.ru/agronomy/article/view/19513">https://agrojournal.rudn.ru/agronomy/article/view/19513</self-uri><abstract xml:lang="en"><p>The present study was undertaken to evaluate the lethal toxicity and stress signs of Flonicamid toward juvenile common carp ( Cyprinus carpio ). The 96 h LC50 values, determined 43.17 mgL-1 by probit analysis in a semi-static system. LC50 24, 48 and 72 h were 47.54, 41.83 and 43.51 mgL-1, respectively. Behavioral changes include hyperexcitement, erratic swimming, dark coloration, loss of equilibrium and lethargy were observed with different intensities. Consequently, mortality rate, stress signs and behavioral changes observed in response to the Flonicamid are dependent to dose and time exposure.</p></abstract><trans-abstract xml:lang="ru"><p>Настоящее исследование было проведено для оценки летальной токсичности и определения симптомов интоксикации флоникамида по отношению к молодому карпу ( Cyprinus carpio ). Средняя летальная концентрация за 96 ч отмечается при 43,17 мг/л с помощью пробит-анализа в полустатической системе. Средняя летальная концентрация через 24, 48 и 72 ч составили 47,54, 41,83 и 43,51 мг/л соответственно. Среди поведенческих изменений преобладали гипервозбуждение, неустойчивое плавание, темная окраска, потеря равновесия и летаргия, которые наблюдались с различной интенсивностью. Следовательно, уровень смертности, стрессовые признаки и поведенческие изменения, наблюдаемые в ответ на прием флоникамида, зависят от дозы и времени воздействия препарата.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Flonicamid</kwd><kwd>lethal concentration</kwd><kwd>Cyprinus carpio</kwd><kwd>intoxication symptoms</kwd><kwd>behavior</kwd><kwd>Cyprinus carpio</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>флоникамид</kwd><kwd>летальная концентрация</kwd><kwd>симптомы интоксикации</kwd><kwd>поведение</kwd></kwd-group><funding-group><award-group><funding-source><institution-wrap><institution xml:lang="en">This work has been supported the Center for International Scientific Studies &amp; Collaboration (CISSC), Ministry of Science Research Technology.</institution></institution-wrap><institution-wrap><institution xml:lang="ru">Данное исследование было проведено при поддержке Центра международных научных исследований и сотрудничества (CISSC) Министерства науки, исследований и технологий Ирана.</institution></institution-wrap></funding-source><award-id></award-id></award-group></funding-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Cho SR, Koo HN, Yoon C, Kim GH. 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