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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">RUDN Journal of Agronomy and Animal Industries</journal-id><journal-title-group><journal-title xml:lang="en">RUDN Journal of Agronomy and Animal Industries</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник Российского университета дружбы народов. Серия: Агрономия и животноводство</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2312-797X</issn><issn publication-format="electronic">2312-7988</issn><publisher><publisher-name xml:lang="en">Peoples’ Friendship University of Russia named after Patrice Lumumba</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">19766</article-id><article-id pub-id-type="doi">10.22363/2312-797X-2022-17-2-203-209</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Veterinary science</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Ветеринария</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Trace element status of highly productive cows in different physiological conditions under increased technogenic load</article-title><trans-title-group xml:lang="ru"><trans-title>Микроэлементный статус высокопродуктивных коров при различном физиологическом состоянии в условиях повышенной техногенной нагрузки</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0354-8149</contrib-id><name-alternatives><name xml:lang="en"><surname>Drozhzhin</surname><given-names>Oleg S.</given-names></name><name xml:lang="ru"><surname>Дрожжин</surname><given-names>Олег Сергеевич</given-names></name></name-alternatives><bio xml:lang="en"><p>Candidate of Biological Sciences, Leading Researcher, Laboratory of toxicology, safety risk assessment of raw materials and products of biological Origin</p></bio><bio xml:lang="ru"><p>кандидат биологических наук, ведущий научный сотрудник лаборатории токсикологии, оценки рисков безопасности сырья и продуктов биологического происхождения</p></bio><email>icrsa@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0730-3680</contrib-id><name-alternatives><name xml:lang="en"><surname>Shipilov</surname><given-names>Valeriy V.</given-names></name><name xml:lang="ru"><surname>Шипилов</surname><given-names>Валерий Валерьевич</given-names></name></name-alternatives><bio xml:lang="en"><p>Engineer for adjustment and testing, Laboratory of toxicology, risk assessment of the safety of raw materials and products of biological origin</p></bio><bio xml:lang="ru"><p>инженер по наладке и испытаниям лаборатории токсикологии, оценки рисков безопасности сырья и продуктов биологического происхождения</p></bio><email>vnivipat@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Russian Research Veterinary Institute of Pathology, Pharmacology and Therapy</institution></aff><aff><institution xml:lang="ru">Всероссийский научно-исследовательский ветеринарный институт патологии, фармакологии и терапии</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2022-06-16" publication-format="electronic"><day>16</day><month>06</month><year>2022</year></pub-date><volume>17</volume><issue>2</issue><issue-title xml:lang="en">VOL 17, NO2 (2022)</issue-title><issue-title xml:lang="ru">ТОМ 17, №2 (2022)</issue-title><fpage>203</fpage><lpage>209</lpage><history><date date-type="received" iso-8601-date="2022-06-16"><day>16</day><month>06</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2022, Drozhzhin O.S., Shipilov V.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2022, Дрожжин О.С., Шипилов В.В.</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="en">Drozhzhin O.S., Shipilov V.V.</copyright-holder><copyright-holder xml:lang="ru">Дрожжин О.С., Шипилов В.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://agrojournal.rudn.ru/agronomy/article/view/19766">https://agrojournal.rudn.ru/agronomy/article/view/19766</self-uri><abstract xml:lang="en"><p style="text-align: justify;">Microelements play a vital role in the maintenance and intensification of metabolic and regulatory processes in the body of animals. For a more complete study of provision of body of highly productive animals with microelements and diagnosis of metabolic disorders, especially under anthropogenic load, it is necessary to conduct biochemical blood tests. The article presents the results of studies on the content of trace elements (iron, copper, zinc, manganese) in the whole blood of cows from two farms in the Voronezh region, one of which (farm 2) is located in an area with increased technogenic load. In whole blood, the content of iron, copper, zinc, and manganese was determined by atomic absorption using a Shimadzu AA-6300 spectrophotometer. Samples were prepared by wet ashing at elevated pressure in a MARS-5 microwave system. Blood samples were taken 2 weeks before calving, one week and one month after calving. A reduced level of copper and zinc was found in animals from both farms throughout the entire study period. The dependence of the content of microelements on the physiological state of animals (before and after calving) was not revealed. It was shown that the content of iron in the blood of highly productive cows from farm 2 was lower throughout the study, and manganese - a week and a month after calving. The amount of manganese in blood of farm 2 animals was less than the lower limit of the physiological norm, while in farm 1 animals its concentration was within the reference normal range.</p></abstract><trans-abstract xml:lang="ru"><p style="text-align: justify;">Значительную роль в поддержании и интенсификации обменных и регуляторных процессов в организме животных играют микроэлементы, являющиеся их активными участниками. Для более полного изучения обеспеченности организма высокопродуктивных животных микроэлементами и диагностики нарушения обмена веществ, особенно в условиях антропогенной нагрузки, необходимо проведение биохимических исследований крови. Приведены результаты исследований по содержанию микроэлементов (железа, меди, цинка, марганца) в цельной крови коров двух хозяйств Воронежской области, одно из которых (хозяйство 2) находится в зоне с повышенной техногенной нагрузкой. В цельной крови определяли содержание железа, меди, цинка и марганца атомно-абсорбционным методом на спектрофотометре Shimadzu AA-6300. Подготовку проб проводили методом мокрого озоления при повышенном давлении в микроволновой системе MARS-5. Пробы крови отбирали за 2 недели до отела, через неделю и месяц после отела. Выявлен пониженный уровень меди и цинка у животных обоих хозяйств на протяжении всего периода исследования. Зависимость содержания микроэлементов от физиологического состояния животных (до и после отела) не выявлена. Показано, что содержание железа в крови высокопродуктивных коров хозяйства 2 было ниже на протяжении всего исследования, а марганца через неделю и месяц после отела. Количество марганца в крови животных хозяйства 2 было меньше нижней границы физиологической нормы, тогда как у животных хозяйства 1 его концентрация находилась в референсных пределах нормы.</p></trans-abstract><kwd-group xml:lang="en"><kwd>cows</kwd><kwd>whole blood</kwd><kwd>trace elements</kwd><kwd>iron</kwd><kwd>copper</kwd><kwd>zinc</kwd><kwd>manganese</kwd><kwd>technogenic load</kwd><kwd>physiological state</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>коровы</kwd><kwd>цельная кровь</kwd><kwd>микроэлементы</kwd><kwd>железо</kwd><kwd>медь</kwd><kwd>цинк</kwd><kwd>марганец</kwd><kwd>техногенная нагрузка</kwd><kwd>физиологическое состояние</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Miroshnikov SA, Skalny AV, Zavyalov OA, Frolov AN, Grabeklis AR. The reference values of hair content of trace elements in dairy cows of Holstein breed. 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