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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">RUDN Journal of Agronomy and Animal Industries</journal-id><journal-title-group><journal-title xml:lang="en">RUDN Journal of Agronomy and Animal Industries</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник Российского университета дружбы народов. Серия: Агрономия и животноводство</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2312-797X</issn><issn publication-format="electronic">2312-7988</issn><publisher><publisher-name xml:lang="en">Peoples’ Friendship University of Russia named after Patrice Lumumba</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">19831</article-id><article-id pub-id-type="doi">10.22363/2312-797X-2022-17-4-484-498</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Animal breeding</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Животноводство</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Reproductive capacity and milk production of cows depending on their physio-logical status during lactation</article-title><trans-title-group xml:lang="ru"><trans-title>Воспроизводительные способности и молочная продуктивность коров в зависимости от физиологического статуса в период лактации</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9021-1404</contrib-id><name-alternatives><name xml:lang="en"><surname>Kornelaeva</surname><given-names>Maria V.</given-names></name><name xml:lang="ru"><surname>Карликова</surname><given-names>Галина Геннадьевна</given-names></name></name-alternatives><bio xml:lang="en"><p>Doctor of Agricultural Sciences, Senior Researcher, Department of Population Genetics and Genetic Fundamentals of Animal Breeding</p></bio><bio xml:lang="ru"><p>доктор сельскохозяйственных наук, старший научный сотрудник отдела популяционной генетики и генетических основ разведения животных</p></bio><email>karlikovagalina@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5674-6694</contrib-id><name-alternatives><name xml:lang="en"><surname>Karlikova</surname><given-names>Galina G.</given-names></name><name xml:lang="ru"><surname>Корнелаева</surname><given-names>Мария Владимировна</given-names></name></name-alternatives><bio xml:lang="en"><p>Postgraduate Student, Junior Researcher, Department of Population Genetics and Genetic Fundamentals of Animal Breeding</p></bio><bio xml:lang="ru"><p>аспирант, младший научный сотрудник отдела популяционной генетики и генетических основ разведения животных</p></bio><email>marikornelaeva@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">L.K. Ernst Federal Research Center for Animal Husbandry</institution></aff><aff><institution xml:lang="ru">Федеральный исследовательский центр животноводства - ВИЖ им. академика Л.К. Эрнста</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2022-12-27" publication-format="electronic"><day>27</day><month>12</month><year>2022</year></pub-date><volume>17</volume><issue>4</issue><issue-title xml:lang="en">VOL 17, NO4 (2022)</issue-title><issue-title xml:lang="ru">ТОМ 17, №4 (2022)</issue-title><fpage>484</fpage><lpage>498</lpage><history><date date-type="received" iso-8601-date="2022-12-27"><day>27</day><month>12</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2022, Kornelaeva M.V., Karlikova G.G.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2022, Карликова Г.Г., Корнелаева М.В.</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="en">Kornelaeva M.V., Karlikova G.G.</copyright-holder><copyright-holder xml:lang="ru">Карликова Г.Г., Корнелаева М.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://agrojournal.rudn.ru/agronomy/article/view/19831">https://agrojournal.rudn.ru/agronomy/article/view/19831</self-uri><abstract xml:lang="en"><p style="text-align: justify;">Due to violation of husbandry, feeding, milking, non-observance of sanitary requirements, especially in postpartum period, cases of endometritis, mastitis and limb diseases in cows increase in conditions of intensive cattle breeding. These diseases adversely affect reproductive and productive qualities of animals, thus causing great financial losses to agribusiness. Therefore, increasing longevity of animals, reducing percentage of their elimination due to various diseases, reducing risk of economically significant diseases in dairy herds by selecting highly productive animals with high resistance to common diseases are relevant. The aim of the research was to study phenotypic relationship between fertility level and milk production of black-motley Holsteinized cows with different diseases at the farm in Moscow region. The research materials were 1234 records of diseases - endometritis, mastitis and limb diseases - obtained from veterinary outpatient logs (2015-2021) of the breeding organization. Information about 5 signs of milk productivity and 3 signs of fertility of the studied population of black-motley Holsteinized dairy cattle was taken from ‘Seleks’ database. According to the results, significant (p &lt; 0.01) increase was observed in sick animals in comparison with healthy ones: number of inseminations per lactation - b y 33.5 %, open days - b y 7.3 %, milk days - b y 4.35 %. Milk yield was higher by 19.4 % (p &lt; 0.01), fat and protein mass fraction - by 0.32 and 0.33 % (p &lt; 0.01), respectively, fat and protein yield - b y 82 and 69 kg (p &lt; 0.01), respectively, compared to healthy animals. When comparing the indices in animals with one, two and three diseases, significant differences were obtained both between the groups with single diseases and complexes. For fertility traits, the indices increased significantly with the number of diseases from 4 to 20 % for individual traits. For milk production traits, there was a tendency for indices to decrease with increasing number of diseases.</p></abstract><trans-abstract xml:lang="ru"><p style="text-align: justify;">В условиях интенсивного скотоводства возрастает вероятность случаев заболевания эндометритом, маститом и болезнями конечностей у коров из-за нарушения технологий содержания, кормления, доения, несоблюдения санитарных требований, в особенности в послеродовой период. Эти заболевания отрицательно сказываются на воспроизводительных и продуктивных качествах животных, нанося тем самым большой финансовый ущерб агробизнесу. Следовательно, вопрос об увеличении долголетия животных, уменьшении процента выбытия их вследствие заболеваний различной природы, а также уменьшении риска экономически значимых заболеваний в молочных стадах посредством отбора и подбора животных с высокой резистентностью к наиболее распространенным болезням высокопродуктивных стад является актуальным. Цель исследований - изучение фенотипической взаимосвязи уровня фертильности и молочной продуктивности коров черно-пестрой голштинизированной породы с разными комплексами заболеваний на примере хозяйства Московской области. Материалами исследований послужили 1234 записи с учтенными заболеваниями: эндометритом, маститом и заболеваниями конечностей, полученные из ветеринарных амбулаторных журналов 2015-2021 гг. племенной организации. Информация о 5 признаках молочной продуктивности и 3 признаках фертильности исследуемой популяции черно-пестрого голштинизированного молочного скота взята из базы данных по разведению молочного скота ИАС «Селэкс». В результате исследований у больных животных в сравнении со здоровыми отмечено достоверное (p &lt; 0,01) увеличение: кратности осеменения в среднем за лактацию в 0,7 раза (33,5 %), сервис-периода - н а 11 дней (7,3 %), дойных дней - н а 16 (4,35 %). В среднем были выше, чем у здоровых животных: удой на 1365 кг, или на 19,4 % (p &lt; 0,01), массовая доля жира и белка - на 0,32 и 0,33 % (p &lt; 0,01) соответственно, выход жира и белка - на 82 и 69 кг (p &lt; 0,01) соответственно. При сравнении показателей у животных с одним, двумя и тремя заболеваниями были получены достоверные различия между группами как с единичными заболеваниями, так и с комплексами. По фертильности показатели достоверно увеличивались с числом заболеваний от 4 до 20 % для отдельных признаков. По признакам молочной продуктивности наблюдалась тенденция снижения показателей с ростом количества заболеваний.</p></trans-abstract><kwd-group xml:lang="en"><kwd>dairy cows</kwd><kwd>health disorders</kwd><kwd>fertility</kwd><kwd>milk productivity</kwd><kwd>Holstein breed</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>дойные коровы</kwd><kwd>нарушение здоровья</kwd><kwd>фертильность</kwd><kwd>молочная продуктивность</kwd><kwd>голштинизированная порода</kwd></kwd-group><funding-group><award-group><funding-source><institution-wrap><institution xml:lang="ru">Исследования проведены при поддержке Министерства науки и высшего образования Российской Федерации, регистрационный номер темы Госзадания 0445-2021-0016.</institution></institution-wrap><institution-wrap><institution xml:lang="en">The research was financially supported by the Ministry of Science and Higher Education of the Russian Federation, State Assignment no. 0445-2021-0016.</institution></institution-wrap></funding-source></award-group></funding-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Grachev VS, Braginets SA, Alekseeva AY. Analysis of the impact of various factors on the productivity and longevity of dairy cattle. Izvesniya Saint-Petersburg State Agrarian University. 2020;(61):73—79. (In Russ.). doi: 10.24411/2078-1318-2020-14073</mixed-citation><mixed-citation xml:lang="ru">Грачев В.С., Брагинец С.А., Алексеева А.Ю. Анализ влияния различных факторов на продуктивность и долголетие молочного скота // Сельскохозяйственные науки: ветеринария и зоотехния. 2020. № 61. С. 73-79. doi: 10.24411/2078-1318-2020-14073</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">Ivanova IP, Grigoriev ME, Pilipchuk VK. Technological aspects of increasing the productive longevity of dairy herds. Molochnokhozayistvenny vestnik. 2020;(2):95—103. (In Russ.).</mixed-citation><mixed-citation xml:lang="ru">Иванова И.П., Григорьев М.Е., Пилипчук В.К. Технологические аспекты повышения продуктивного долголетия молочных стад // Молочнохозяйственный вестник. 2020. № 2 (38). С. 95-103.</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">Karlikov DV. Selektsiya skota na ustoichivost’ k zabolevaniyam [Selection of livestock for disease resistance]. Moscow: Rossel’khozizdat publ.; 1984. (In Russ.).</mixed-citation><mixed-citation xml:lang="ru">Карликов Д.В. Селекция скота на устойчивость к заболеваниям. М.: Россельхозиздат, 1984. 191 с.</mixed-citation></citation-alternatives></ref><ref id="B4"><label>4.</label><citation-alternatives><mixed-citation xml:lang="en">Dallago GM, Wade KM, Cue RI, McClure JT, Lacroix R, Pellerin D, et al. Keeping dairy cows for longer: a critical literature review on dairy cow longevity in high milk-producing countries. Animals. 2021;11(3):808. doi: 10.3390/ani11030808</mixed-citation><mixed-citation xml:lang="ru">Dallago G.M., Wade K.M., Cue R.I., McClure J.T., Lacroix R., Pellerin D., Vasseur E. Keeping dairy cows for longer: a critical literature review on dairy cow longevity in high milk-producing countries // Animals. 2021. Vol. 11. № 33. P. 808. doi: 10.3390/ani11030808</mixed-citation></citation-alternatives></ref><ref id="B5"><label>5.</label><citation-alternatives><mixed-citation xml:lang="en">Lindgren MA. Factors affecting reproductive performance and health in dairy cows in Tajikistan. Uppsala; 2017.</mixed-citation><mixed-citation xml:lang="ru">Lindgren M.A. Factors affecting reproductive performance and health in dairy cows in Tajikistan. Uppsala: Veterinary Medicine, 2017.</mixed-citation></citation-alternatives></ref><ref id="B6"><label>6.</label><citation-alternatives><mixed-citation xml:lang="en">Torres E, Mellado M, Leyva C, García JE, Véliz FG, Hernández-Bustamante J. Serum metabolites and body condition score associated with metritis, endometritis, ketosis, and mastitis in Holstein cows. Pesquisa Agropecuaria Brasileira. 2020;55:e01308. doi: 10.1590/S1678-3921.pab2020.v55.01308</mixed-citation><mixed-citation xml:lang="ru">Torres E., Mellado M., Leyva C., García J.E., Véliz F.G., Hernández-Bustamante J. Serum metabolites and body condition score associated with metritis, endometritis, ketosis, and mastitis in Holstein cows // Pesquisa Agropecuaria Brasileira. 2020. Vol. 55. P. 1-10. doi: 10.1590/S1678-3921.pab2020.v55.01308</mixed-citation></citation-alternatives></ref><ref id="B7"><label>7.</label><citation-alternatives><mixed-citation xml:lang="en">May K, Sames L, Scheper C, König S. Genomic loci and genetic parameters for uterine diseases in first-parity Holstein cows and associations with milk production and fertility. Journal of Dairy Science. 2022;105(1):509—524. doi: 10.3168/jds.2021-20685</mixed-citation><mixed-citation xml:lang="ru">May K., Sames L., Scheper C., König S. Genomic loci and genetic parameters for uterine diseases in first-parity Holstein cows and associations with milk production and fertility // Journal of Dairy Science. 2022. Vol. 105. № 1. P. 509-524. doi: 10.3168/jds.2021-20685</mixed-citation></citation-alternatives></ref><ref id="B8"><label>8.</label><citation-alternatives><mixed-citation xml:lang="en">Paiano RB, Bonilla J, Pugliesi G, Moreno AM, Baruselli PS. Assessment of clinical and subclinical endometritis impacts on the reproductive performance and milk production of dairy cows in Brazilian herds. Research Square. 2022:1—12. doi: 10.21203/rs.3.rs-1585629/v1</mixed-citation><mixed-citation xml:lang="ru">Paiano R.B., Bonilla J., Pugliesi G., Moreno A.M., Baruselli P.S. Assessment of clinical and subclinical endometritis impacts on the reproductive performance and milk production of dairy cows in Brazilian herds // Research Square (internet resource). 2022. P. 1-12. doi: 10.21203/rs.3.rs-1585629/v1</mixed-citation></citation-alternatives></ref><ref id="B9"><label>9.</label><citation-alternatives><mixed-citation xml:lang="en">Rodin NV. Verifikatsiya diagnoza i terapiya korov v nachale laktatsii pri sindrome «mastit-endometrit» [Verification of diagnosis and therapy of cows with «mastitis-endometritis» syndrome at the beginning of lactation]. Saratov; 2016. (In Russ.).</mixed-citation><mixed-citation xml:lang="ru">Родин Н.В. Верификация диагноза и терапия коров в начале лактации при синдроме «маститэндометрит»: дис. … канд. с. - х. наук. Саратов, 2016.</mixed-citation></citation-alternatives></ref><ref id="B10"><label>10.</label><citation-alternatives><mixed-citation xml:lang="en">Purba FY, Suzuki N, Isobe N. Association of endometritis and ovarian follicular cyst with mastitis in dairy cows. Journal of Veterinary Medical Science. 2021;83(2):338—343. doi: 10.1292/jvms.20-0652</mixed-citation><mixed-citation xml:lang="ru">Purba F.Y., Suzuki N., Isobe N. Association of endometritis and ovarian follicular cyst with mastitis in dairy cows // Journal of Veterinary Medical Science. 2021. Vol. 83. № 2. P. 338-343. doi: 10.1292/jvms.20-0652</mixed-citation></citation-alternatives></ref><ref id="B11"><label>11.</label><citation-alternatives><mixed-citation xml:lang="en">Wang N, Zhou C, Basang W, Zhu Y, Wang X, Li C, Chen L, Zhou X. Mechanisms by which mastitis affects reproduction in dairy cow: a review. Reproduction in Domestic Animals. 2021;56(9):1165—1175. doi: 10.1111/rda.13953</mixed-citation><mixed-citation xml:lang="ru">Wang N., Zhou Ch., Basang W., Zhu Y., Wang X., Li Ch., Chen L., Zhou X. Mechanisms by which mastitis affects reproduction in dairy cow: a review // Reproduction in Domestic Animals. 2021. Vol. 56. № 9. P. 1165-1175. doi: 10.1111/rda.13953</mixed-citation></citation-alternatives></ref><ref id="B12"><label>12.</label><citation-alternatives><mixed-citation xml:lang="en">Smulski S, Gehrke M, Libera K, Cieslak A, Huang H, Patra AK, Szumacher-Strabel M. Effects of various mastitis treatments on the reproductive performance of cows. BMC Veterinary Research. 2020;16:99. doi: 10.1186/s12917-020-02305-7</mixed-citation><mixed-citation xml:lang="ru">Smulski S., Gehrke M., Libera K., Cieslak A., Huang H., Patra A.K., Szumacher-Strabel M. Effects of various mastitis treatments on the reproductive performance of cows // BMC Veterinary Research. 2020. Vol.</mixed-citation></citation-alternatives></ref><ref id="B13"><label>13.</label><citation-alternatives><mixed-citation xml:lang="en">Ratanapob N, Thiangtum W, Rukkwamsuk T, Srisomrun S, Panneum S, Arunvipas P. The relationship between lameness and reproductive performance in dairy cows raised in small holder farms, Thailand. Songklanakarin Journal of Science and Technology. 2020;42(4):766—770.</mixed-citation><mixed-citation xml:lang="ru">№ 16. P. 1-10. doi: 10.1186/s12917-020-02305-7</mixed-citation></citation-alternatives></ref><ref id="B14"><label>14.</label><citation-alternatives><mixed-citation xml:lang="en">Skachkova OA, Brigida AV. Impact of genomic selection on health improvement of high-yielding cows. Veterinaria i kormlenie. 2021;(6):48—50. (In Russ.). doi: 10.30917/ATT-VK-1814-9588-2021-6-12</mixed-citation><mixed-citation xml:lang="ru">Ratanapob N., Thiangtum W., Rukkwamsuk Th., Srisomrun S., Panneum S., Arunvipas P. The relationship between lameness and reproductive performance in dairy cows raised in small holder farms, Thailand // Songklanakarin Journal of Science and Technology. 2020. Vol. 42. № 4. P. 766-770.</mixed-citation></citation-alternatives></ref><ref id="B15"><label>15.</label><citation-alternatives><mixed-citation xml:lang="en">Smirnova OV. Selection for resistance to hoof disorders in dairy cattle populations in the Nordic countries. Genetics and breeding of animals. 2017;(2):73—78. (In Russ.).</mixed-citation><mixed-citation xml:lang="ru">Скачкова О.А., Бригида А.В. Влияние геномной селекции на улучшение здоровья у высокоудойных коров // Ветеринария и кормление. 2021. № 6. С. 48-50. doi: 10.30917/ATT-VK-1814-9588-2021-6-12</mixed-citation></citation-alternatives></ref><ref id="B16"><label>16.</label><citation-alternatives><mixed-citation xml:lang="en">Rostellato R, Promp J, Leclerc H, Mattalia S, Friggens NC, Boichard D, et al. Influence of production, reproduction, morphology, and health traits on true and functional longevity in French Holstein cows. Journal of Dairy Science. 2021;104(12):12664—12678. doi: 10.3168/jds.2020-19974</mixed-citation><mixed-citation xml:lang="ru">Смирнова О.В. Селекция на устойчивость к заболеваниям копыт в популяциях молочного скота в странах Северной Европы // Генетика и разведение животных. 2017. № 2. С. 73-78.</mixed-citation></citation-alternatives></ref><ref id="B17"><label>17.</label><mixed-citation>Rostellato R., Promp J., Leclerc H., Mattalia S., Friggens N.C., Boichard D., Ducrocq V. Influence of production, reproduction, morphology, and health traits on true and functional longevity in French Holstein cows // Journal of Dairy Science. 2021. Vol. 104. № 12. P. 12664-12678. doi: 10.3168/jds.2020-19974</mixed-citation></ref></ref-list></back></article>
