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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">RUDN Journal of Agronomy and Animal Industries</journal-id><journal-title-group><journal-title xml:lang="en">RUDN Journal of Agronomy and Animal Industries</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник Российского университета дружбы народов. Серия: Агрономия и животноводство</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2312-797X</issn><issn publication-format="electronic">2312-7988</issn><publisher><publisher-name xml:lang="en">Peoples’ Friendship University of Russia named after Patrice Lumumba</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">20070</article-id><article-id pub-id-type="doi">10.22363/2312-797X-2024-19-3-517-529</article-id><article-id pub-id-type="edn">CLBMOC</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Veterinary science</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Ветеринария</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Clinical efficacy of epidural injection of betamethasone in dogs with lumbosacral stenosis</article-title><trans-title-group xml:lang="ru"><trans-title>Клиническая эффективность эпидурального введения бетаметазона при пояснично-крестцовом стенозе у собак</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2567-272X</contrib-id><contrib-id contrib-id-type="spin">3104-7566</contrib-id><name-alternatives><name xml:lang="en"><surname>Yagnikov</surname><given-names>Sergey A.</given-names></name><name xml:lang="ru"><surname>Ягников</surname><given-names>Сергей Александрович</given-names></name></name-alternatives><bio xml:lang="en"><p>Doctor of Veterinary Sciences, Professor, Head of VetProfAlliance Veterinary Surgery Centers; Professor, Department of Veterinary Medicine, RUDN University</p></bio><bio xml:lang="ru"><p>доктор ветеринарных наук, профессор, руководитель центра ветеринарной хирургии «ВетПрофАльянс» ; профессор департамента ветеринарной медицины, Российский университет дружбы народов</p></bio><email>yagnikovorc@yandex.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-0329-9748</contrib-id><name-alternatives><name xml:lang="en"><surname>Barseghyan</surname><given-names>Lusine S.</given-names></name><name xml:lang="ru"><surname>Барсегян</surname><given-names>Лусинэ Самвеловна</given-names></name></name-alternatives><bio xml:lang="en"><p>Candidate of Veterinary Sciences, Veterinarian-surgeon</p></bio><bio xml:lang="ru"><p>кандидат ветеринарных наук, ветеринарный врач-хирург московского филиала центра ветеринарной хирургии</p></bio><email>vetprophy@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">VetProfAlliance Veterinary Surgery Centers</institution></aff><aff><institution xml:lang="ru">Центр ветеринарной хирургии «ВетПрофАльянс»</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">RUDN University</institution></aff><aff><institution xml:lang="ru">Российский университет дружбы народов</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2024-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2024</year></pub-date><volume>19</volume><issue>3</issue><issue-title xml:lang="en">VOL 19, NO3 (2024)</issue-title><issue-title xml:lang="ru">ТОМ 19, №3 (2024)</issue-title><fpage>517</fpage><lpage>529</lpage><history><date date-type="received" iso-8601-date="2024-12-09"><day>09</day><month>12</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Yagnikov S.A., Barseghyan L.S.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, Ягников С.А., Барсегян Л.С.</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Yagnikov S.A., Barseghyan L.S.</copyright-holder><copyright-holder xml:lang="ru">Ягников С.А., Барсегян Л.С.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://agrojournal.rudn.ru/agronomy/article/view/20070">https://agrojournal.rudn.ru/agronomy/article/view/20070</self-uri><abstract xml:lang="en"><p>Results of conservative treatment of degenerative lumbosacral stenosis in dogs are presented. For the first time, clinical efficacy of epidural injection of anti-inflammatory drug Diprospan (betamethasone) in dogs with lumbosacral stenosis was shown. 32 animals were treated at VetProfAlliance Veterinary Surgery Center from 2023 to June 2024. Comparable data in case histories and feedback for evaluating treatment outcomes were established with the owners of 22 dogs. 22 case histories were analyzed. To exclude possible concomitant orthopedic pathologies, X-ray examination of knee and hock joints in mediolateral projection and hip joints in ventrodorsal projection was performed. Patients with discospondylitis at lumbosacral level were excluded from the study group. All dogs with lumbosacral stenosis belonged to large and giant dog breeds. The age of clinical symptoms is from 6 to 11 years old, and breed variability to this disease was also noted. Males predominate by gender - 59% (13/22). At the same time, 69% (9/13) of males were castrated and 78% (7/9) of females were sterilized. 32% (7/22) of dogs in this group were obese, and 50% (11/22) were overweight. Studies have found that Diprospan injections with 20…30 days interval can completely neutralize neurological symptoms in 50% of dogs with 1…4 degrees of neurological disorders caused by lumbosacral stenosis. In 22 out of 32 dogs, the result of treatment was assessed as positive with improvement in condition or achievement of complete remission.</p></abstract><trans-abstract xml:lang="ru"><p>Приведены результаты консервативного лечения дегенеративного пояснично-крестцовый стеноза (ДПКС) у собак. Впервые показана клиническая эффективность эпидурального введения противовоспалительного препарата Дипроспан (бетаметазон) при ДПКС. Выборка животных для анализа результатов лечения составила 32 пациента, которым с 2023 по июнь 2024 г. проводили лечение в центре ветеринарной хирургии «ВетПрофАльяс. Сопоставимые данные в историях болезни и обратная связь для оценки результатов лечения была установлена с владельцами 22 пациентов. Анализу подвергнуты 22 истории болезни. Для исключения возможных сопутствующих ортопедических патологий выполняли рентгенографическое исследование коленного и скакательного суставов в медиолатеральной проекции и тазобедренных суставов в вентродорсальной проекции. Из группы исследования исключили пациентов с дискоспондилитом на уровне пояснично-крестцового отдела. Все собаки с пояснично-крестцовым стенозом относились к крупным и гигантским породам собак. Возраст проявления клинической симптоматики - от 6 до 11 лет, также отмечена породная вариабильность к данному заболеванию. По половому признаку превалируют самцы - 59 % (13 из 22). При этом 69 % (9 из 13) самцов были кастрированы и 78 % (7 из 9) самок стерилизованы. Ожирение в данной группе наблюдения имели 32 % (7 из 22) собак, а избыточную массу тела - 50 % (11 из 22). Исследованиями установлено, что инъекции дипроспана с интервалом 20…30 суток могут полностью нивелировать неврологические симптомы у 50 % собак с 1-4-й степенью неврологических расстройств, вызванных пояснично-крестцовым стенозом. У 22 из 32 пациентов результат лечения был оценен как положительный с улучшением состояния пациента или достижений полной ремиссии.</p></trans-abstract><kwd-group xml:lang="en"><kwd>degenerative lumbosacral stenosis</kwd><kwd>epidural injections</kwd><kwd>treatment</kwd><kwd>long-term results</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>дегенеративный пояснично-крестцовый стеноз</kwd><kwd>эпидуральные инъекции</kwd><kwd>лечение</kwd><kwd>отдаленные результаты</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Suwankong N, Meij BP, Voorhout G, De Boer AH, Hazewinkel HAW. 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