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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">RUDN Journal of Agronomy and Animal Industries</journal-id><journal-title-group><journal-title xml:lang="en">RUDN Journal of Agronomy and Animal Industries</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник Российского университета дружбы народов. Серия: Агрономия и животноводство</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2312-797X</issn><issn publication-format="electronic">2312-7988</issn><publisher><publisher-name xml:lang="en">Peoples’ Friendship University of Russia named after Patrice Lumumba</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">20250</article-id><article-id pub-id-type="doi">10.22363/2312-797X-2025-20-3-497-508</article-id><article-id pub-id-type="edn">YFWVUQ</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Veterinary science</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Ветеринария</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Clinical features of brain tumors in dogs in the Moscow region: a retrospective study</article-title><trans-title-group xml:lang="ru"><trans-title>Клинические особенности опухолей головного мозга у собак в Московском регионе: ретроспективное исследование</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-5637-2828</contrib-id><name-alternatives><name xml:lang="en"><surname>Glazov</surname><given-names>Nikolay A.</given-names></name><name xml:lang="ru"><surname>Глазов</surname><given-names>Николай Александрович</given-names></name></name-alternatives><bio xml:lang="en"><p>Veterinarian, Veterinary Oncology Research Center “Biocontrol”; postgraduate student, Department of Veterinary Medicine, RUDN University</p></bio><bio xml:lang="ru"><p>ветеринарный врач, Ветеринарный онкологический научный центр «Биоконтроль» ; аспирант департамента ветеринарной медицины, Российский университет дружбы народов</p></bio><email>nikolayglazovvet@gmail.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0036-3402</contrib-id><contrib-id contrib-id-type="spin">2726-8270</contrib-id><name-alternatives><name xml:lang="en"><surname>Vatnikov</surname><given-names>Yuri A.</given-names></name><name xml:lang="ru"><surname>Ватников</surname><given-names>Юрий Анатольевич</given-names></name></name-alternatives><bio xml:lang="en"><p>Doctor of Veterinary Sciences, Professor, Director of the Department of Veterinary Medicine, Agrarian and Technological Institute</p></bio><bio xml:lang="ru"><p>доктор ветеринарных наук, профессор, директор департамента ветеринарной медицины агротехнологического института</p></bio><email>vatnikov@yandex.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5278-1641</contrib-id><name-alternatives><name xml:lang="en"><surname>Yakunina</surname><given-names>Marina N.</given-names></name><name xml:lang="ru"><surname>Якунина</surname><given-names>Марина Николаевна</given-names></name></name-alternatives><bio xml:lang="en"><p>Doctor of Veterinary Sciences, Head of the Oncology Department</p></bio><bio xml:lang="ru"><p>доктор ветеринарных наук, заведующий отделением онкологии</p></bio><email>irsovet@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Biocontrol Veterinary Oncology Research Center</institution></aff><aff><institution xml:lang="ru">Ветеринарный онкологический научный центр «Биоконтроль»</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">RUDN University</institution></aff><aff><institution xml:lang="ru">Российский университет дружбы народов</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2025-11-15" publication-format="electronic"><day>15</day><month>11</month><year>2025</year></pub-date><volume>20</volume><issue>3</issue><issue-title xml:lang="en">Varietal breeding — selection and retention of agronomic traits</issue-title><issue-title xml:lang="ru">Сортовая селекция — отбор и закрепление хозяйственно ценных признаков</issue-title><fpage>497</fpage><lpage>508</lpage><history><date date-type="received" iso-8601-date="2025-11-18"><day>18</day><month>11</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Glazov N.A., Vatnikov Y.A., Yakunina M.N.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Глазов Н.А., Ватников Ю.А., Якунина М.Н.</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Glazov N.A., Vatnikov Y.A., Yakunina M.N.</copyright-holder><copyright-holder xml:lang="ru">Глазов Н.А., Ватников Ю.А., Якунина М.Н.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://agrojournal.rudn.ru/agronomy/article/view/20250">https://agrojournal.rudn.ru/agronomy/article/view/20250</self-uri><abstract xml:lang="en"><p>For the first time in the history of Russian veterinary medicine, a retrospective analysis of the clinical features of brain tumors (BT) in dogs was carried out. The study was conducted in the Moscow region in 2018-2024 on the basis of the Biocontrol veterinary clinic. The aim of the study is to determine the frequency, localization and clinical manifestations of BT. The data of 54,142 dogs were analyzed, of which 150 had BT (1.2% of oncological cases, 0.28% of the total number of patients). The average age was 9.4 years. Most often, BT was recorded in cross-breed, French bulldogs, Cane Corso and German shepherds. Brachycephalic breeds showed a predisposition to intra-axial lesions, mesocephalic to extra-axial. There was no gender predisposition. The main clinical manifestations included convulsions, ataxia, paresis and changes in consciousness depending on the location of the tumor. The median tumor volume was 6 cm³ for extra-axial and 9.4 cm³ for intra-axial lesions. Histological verification was performed in 23 patients. Diagnosis was carried out using MRI (1.5 Tesla), histology and immunohistochemistry. The study showed the need for histological analysis of BT for accurate typing of lesions and emphasized the importance of developing methods of imaging and invasive diagnosis in veterinary medicine. The data obtained partially differ from foreign ones, which is due to the difference in the breed sampling of the dog population. Unique results can serve as a basis for the development of standardized protocols for the diagnosis and treatment of canine BT.</p></abstract><trans-abstract xml:lang="ru"><p>Впервые в истории российской ветеринарии осуществлен ретроспективный анализ клинических особенностей опухолей головного мозга (ОГМ) у собак. Исследование проведено в Московском регионе в 2018-2024 гг. на базе ветеринарной клиники «Биоконтроль». Цель исследования - определение частоты, локализации и клинических проявлений ОГМ. Проанализированы данные 54142 собак, из которых у 150 выявлены ОГМ (1,2 % от онкологических случаев, 0,28 % от общего числа пациентов). Средний возраст составил 9,4 года. Наиболее часто ОГМ регистрировали у метисов, французских бульдогов, кане-корсо и немецких овчарок. Брахицефалические породы показали предрасположенность к интрааксиальным поражениям, мезоцефалы - к экстрааксиальным. Половая предрасположенность отсутствовала. Основные клинические проявления включали судороги, атаксию, парезы и изменения сознания в зависимости от локализации опухоли. Медиана объема опухолей составила 6 см³ для экстрааксиальных и 9,4 см³ для интрааксиальных поражений. Гистологическая верификация выполнена у 23 пациентов. Диагностику проводили с использованием МРТ (1,5 Тесла), гистологии и иммуногистохимии. Исследование показало необходимость гистологического анализа ОГМ для точного типирования поражений и подчеркнуло важность развития методов визуализации и инвазивной диагностики в ветеринарии. Полученные данные частично отличаются от зарубежных, что обусловлено различием породного состава поголовья собак. Уникальные результаты могут служить базой для разработки стандартизированных протоколов диагностики и лечения ОГМ у собак.</p></trans-abstract><kwd-group xml:lang="en"><kwd>veterinary medicine</kwd><kwd>oncology</kwd><kwd>glioma</kwd><kwd>meningioma</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>ветеринария</kwd><kwd>онкология</kwd><kwd>глиома</kwd><kwd>менингиома</kwd></kwd-group><funding-group/></article-meta><fn-group/></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Hayes HM, Priester WA Jr, Pendergrass TW. Occurrence of nervous-tissue tumors in cattle, horses, cats and dogs. International Journal of Cancer. 1975;15(1):39–47. doi: 10.1002/ijc.2910150106</mixed-citation><mixed-citation xml:lang="ru">Hayes HM, Priester WA Jr, Pendergrass TW. Occurrence of nervous-tissue tumors in cattle, horses, cats and dogs. 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