Local and general effects of injection of medicinal forms of enrofloxacin with colistin

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Abstract

The carried out research of local - irritant, skin - resorvent and allergic effect of injection form of drug induding enrofloxacin and colistin in animals. It has slight irritant effect on the skin and doesn't have any skin - resorvent and allergic properties. The influence of composition of enrofloxacin with colistin on the physiological status of animals. It was found that an intramuscular injection of the drug in doses of 0,5 and 1,0 ml per 10 kg bodyweight doesn't have any negative impact on the overall condition of laboratory animals, does not alter the morphological and biochemical indices of their blood. Exchange of drug in a therapeutic dose does not change.

About the authors

V I Parshina

Moscow State Academy of Veterinary Medicine and Biotechnology

Кафедра фармакологии и токсикологии; Московская государственная академияветеринарной медицины и биотехнологии; Moscow State Academy of Veterinary Medicine and Biotechnology

V E Abramov

All-Russian State Center for Qualities and Standardizations of Medicinal MeansFor Animals and Forages (VGNKI)

Отдел качества и стандартизации фармакологических лекарственных средствдля животных и биологически-активных препаратов; Всероссийский государственный центр качества и стандартизациилекарственных средств для животных и кормов (ФГУ ВГНКИ); All-Russian State Center for Qualities and Standardizations of Medicinal MeansFor Animals and Forages (VGNKI)

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Copyright (c) 2009 Паршина В.И., Абрамов В.Е.

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