HISTOARCHITECTURE OF THE THYROID GLAND IN PIGLETS WITH HYPOTROPHY AND AFTER THE COURSE OF MEDICAL CORRECTION

Antenatal malnutrition is a condition characterized by both a weight loss in animals and a change in the morphofunctional characteristics of the internal organs, particularly the incompleteness of the thyroid gland structure that will have a direct impact on the further growth and development of animals. Therefore, the aim of the research was to establish the patterns of histostructure of the thyroid gland inhypotrophic piglets and piglets after prenatal correction of hypotrophy considering their age. The study was performed on piglets of the large white breed. The study material was the thyroid gland of hypotrophic piglets and piglets after prenatal correction with Sedimin at 1, 5, 15 and 30 days of age. The main methods of study: histological, morphometric and statistical data processing. According to the research results, a thickening of the connective tissue capsule of the thyroid gland in newborns and five-day-old hypotrophic piglets was established in relation to fifteen and thirty-day-old ones. The average diameter of the follicle is at a relatively equal level during all periods of the study, the colloid acquired a “foamy” appearance on the fifth and fifteenth day. The form of thyrocytes and their nuclei changed with age from flattened to cubic. Cell-tissue composition of the thyroid gland of piglets after prenatal correction of malnutrition is functionally active. On the first and fifth days the capsule of the organ was thinned, by the end of the study its thickness increased markedly. The diameter of the follicles of the thyroid gland decreased from the neonatal period to the thirtieth day. Throughout the experiment, the structure of the colloid changed in the follicle lumen from homogeneous consistency to “frothy” by the end of the experiment. At the beginning of the experiment, both flattened and cubic-shape epithelial cells were observed in the parenchyma of the thyroid gland, by the thirtieth day it was stably cubic. The nuclei of thyrocytes are mostly spherical and hypochromic. In conclusion, it is worth noting that in hypotrophic piglets in the neonatal period and in the five-day age, the incompleteness of the structure of the thyroid gland was observed, the further morphological reorganization reached by the thirtieth day. The medication “Sedimin” had a positive effect on the body of pigs, reducing the degree of development of malnutrition and contributing to the adequate organoand histogenesis, including the thyroid gland.