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Monitoring in biochemical parameters of blood serum of calves against the background of the use of betulin-containing feed additive
- Authors: Gnezdilova L.A.1, Muradyan Z.Y.1, Kruglova Y.S.1, Rozinsky S.M.1
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Affiliations:
- Moscow State Academy of Veterinary Medicine and Biotechnology - MBA named after K.I. Skryabin
- Issue: Vol 20, No 1 (2025): Therapeutic case of animal welfare
- Pages: 12-26
- Section: Therapeutic case of animal welfare
- URL: https://agrojournal.rudn.ru/agronomy/article/view/20164
- DOI: https://doi.org/10.22363/2312-797X-2025-20-1-12-26
- EDN: https://elibrary.ru/HAVFSP
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Abstract
The studies were conducted at the dairy complexes of the breeding farm of the Agricultural Enterprise Kolkhoz “Soznatelnyˮ, Zubtsovsky District, Tver Region, by the Department of Disease Diagnostics, Therapy, Obstetrics and Reproduction of Animals and the Medical and Diagnostic Center of the Federal State Budgetary Educational Institution of Higher Education Moscow State Academy of Veterinary Medicine and Biotechnology - Moscow State Academy of Veterinary Medicine named after K.I. Skryabin. Betulin-containing feed additive was given to fiveand ten-month-old calves of the experimental groups orally at a dose of 10 mg/kg of weight with water individually once a day for 14 days. To assess the effect of betulin on the body of calves, as well as to exclude concomitant diseases, a clinical study of al[poiuy’lkhgfdsl experimental animals and a biochemical analysis of blood serum were conducted at the beginning and end of the experiment. The study presents the results of clinical trials of a feed additive containing the natural adaptogen betulin. The effect of betulin-containing feed additive on the biochemical parameters of the blood serum of breeding calves and highly productive dairy cattle was studied. It was established that the use of betulin-containing feed additive to calves of five and ten months of age orally at a dose of 10 mg/kg of weight with water individually 1 time per day for 14 days, normalizes the level of bilirubin in the blood serum, alanine aminotransferase and aspartate aminotransferase, alkaline phosphatase lactate dehydrogenase. By the end of the experiment, the calves of the experimental group also showed an increase in the level of total serum protein within the physiological norm. The results obtained indicate that the use of betulin-containing feed additive according to the specified scheme has an anti-inflammatory, cardioand hepatoprotective effect. An increase in the amount of total protein in calves after using the feed additive indicates a compensatory increase in the synthesis of globulin fraction proteins.
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.About the authors
Larisa A. Gnezdilova
Moscow State Academy of Veterinary Medicine and Biotechnology - MBA named after K.I. Skryabin
Author for correspondence.
Email: lag22004@mail.ru
ORCID iD: 0000-0003-1007-3441
SPIN-code: 2376-1425
Doctor of Veterinary Sciences, Professor, Head of the Department of Disease Diagnostics, Therapy, Obstetrics and Reproduction of Animals
23 Academician Skryabin st., Moscow, 109472, Russian FederationZhora Yu. Muradyan
Moscow State Academy of Veterinary Medicine and Biotechnology - MBA named after K.I. Skryabin
Email: zh_muradyan@mail.ru
ORCID iD: 0000-0003-2516-7627
SPIN-code: 4892-9182
Candidate of Biological Sciences, Associate Professor of the Department of Disease Diagnostics, Therapy, Obstetrics and Reproduction of Animals
23 Academician Skryabin st., Moscow, 109472, Russian FederationYulia S. Kruglova
Moscow State Academy of Veterinary Medicine and Biotechnology - MBA named after K.I. Skryabin
Email: y7272@mail.ru
ORCID iD: 0000-0003-2953-0745
SPIN-code: 7902-6183
Candidate of Veterinary Sciences, Associate Professor of the Department of Disease Diagnostics, Therapy, Obstetrics and Reproduction of Animals
23 Academician Skryabin st., Moscow, 109472, Russian FederationSerafim M. Rozinsky
Moscow State Academy of Veterinary Medicine and Biotechnology - MBA named after K.I. Skryabin
Email: ser.roz1@yandex.ru
ORCID iD: 0009-0001-1937-6919
SPIN-code: 8705-3851
assistant of the department of diagnostics of diseases, therapy, obstetrics and reproduction of animals
23 Academician Skryabin st., Moscow, 109472, Russian FederationReferences
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