Testing two forms of rodenticide baits based on brodifacoum in vitro on Norway rats Rattusnorvegicus

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Abstract

The chemical method is the most common to control rodents. Fast acting rodenticides (zinc phosphide and krysid) and slow-acting rodenticides divided into first- and second-g eneration anticoagulants are used for deratization practice. The aim of the study was to evaluate the results of rodenticidal activity of brodifacum for two forms of rodenticidal baits in order to control rodents in settlements and adjacent territories, on agricultural land and reduce their harm. In case of high numbers, they carry such dangerous diseases as plague, typhoid fever, paratyphs, encephalitis, rabies, tuberculosis, tularemia, etc. Fleas and ticks parasitizing mouse-like rodents transmit pathogens to pets and humans. The economic damage caused by rodents is high. They destroy and spoil food and fodder, destroy the seedlings of agricultural crops. In a year, a gray rat eats 20…24 kg of food and pollutes 10 times more products. In total, two forms of baits based on brodifacoum were prepared against rodents. We proposed and tested the rodenticidal activity of the forms of baits developed in loose and soft forms. The assessment established that both forms had high biological activity, reaching 90.17 and 89.67 %. Consumption rates of poisoned baits in the form of soft briquettes were lower compared to grain baits, showing high efficiency and saving the food base for preparation of poisoned rodenticidal baits.

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Table 1. Dynamics of eatability of grain bait based on rodenticide  containing brodifacoum active ingredient

No

Gender

Initial amount of feed, g

Amount of bait eaten by day, g

1

2

3

4

5

E

C

E

C

E

C

E

C

E

C

E

C

1

30

89

10.8

13.5

15.18

0,43

0

0

0

0

х

х

2

40

87

32.3

14.1

4.84

2,62

0

0

х

х

х

х

Average

35

88

21,55

13.8

10.01

1.52

0

0

0

х

х

х

Note. E — experiment; C — control; х — rat death.

Table 2. Dynamics of eatability of soft briquette based on rodenticide containing brodifacoum active ingredient

No

Gender

Initial amount of feed, g

Amount of bait eaten by day, g

1

2

3

4

5

E

C

E

C

E

C

E

C

E

C

E

C

3

21

111

10

8.6

7.18

4,7

0

0

0

0

х

х

4

16

105

16

9.2

14,26

0

0

0

0

х

х

Average

18,5

108

13

8.9

3.59

9.48

0

0

0

0

х

х

Note. E — experiment; C — control; х — rat death.

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About the authors

Sergey V. Ryabov

Research Institute for Systems Biology and Medicine

Email: ryabovsv@mail.ru
ORCID iD: 0000-0002-7863-7576

Leading Researcher, Head of the Laboratory of Experimental Models

18 Nauchny driveway, Moscow, 117246, Russian Federation

Valentin V. Vvedensky

RUDN University

Email: vaval-ved@yandex.ru
ORCID iD: 0000-0002-2977-2616

Candidate of Agricultural Sciences, Associate Professor, Agrobiotechnology Department, Agrarian and Technological Institute

8 Miklukho-Maklaya st., Moscow, 117198, Russian Federation

Tatyana V. Dolzhenko

Saint Petersburg State Agrarian University

Email: dolzhenkotv@mail.ru
ORCID iD: 0000-0003-4139-2664

Doctor of Biological Sciences, Professor, Department of Plant Protection and Quarantine

2 Peterburgskoye Highway, Pushkin, St. Petersburg, 196601, Russian Federation

Ranim Karrijow

RUDN University

Author for correspondence.
Email: 1042205065@rudn.ru
ORCID iD: 0009-0009-9405-5136

Graduate Student, Agrobiotechnology Department, Agrarian and Technological Institute

8 Miklukho-Maklaya st., Moscow, 117198, Russian Federation

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Copyright (c) 2023 Ryabov S.V., Vvedensky V.V., Dolzhenko T.V., Karrijow R.

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