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Influence of succinic acid Acidum succinicum on chinchilla growth in postembryonic period
- Authors: Golovacheva N.A.1, Selivanova I.R.1, Chichenkova M.A.1, Filatova P.A.1, Antonova V.S.1
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Affiliations:
- K.G. Razumovsky Moscow State University of Technologies and Management
- Issue: Vol 18, No 3 (2023)
- Pages: 385-398
- Section: Animal breeding
- URL: https://agrojournal.rudn.ru/agronomy/article/view/19927
- DOI: https://doi.org/10.22363/2312-797X-2023-18-3-385-398
- EDN: https://elibrary.ru/NJKKSM
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Abstract
In animal husbandry, special attention is paid to biological additives and natural metabolites used in the development of feeds that ensure productivity of animals and increase resistance to adverse environmental factors. Such additives actively influence energy metabolism and do not harm even in case of an overdose, due to the absence of xenobiotic effects inherent in a large number of synthetic drugs. The purpose of the research was to study growth dynamics of chinchillas against the background of drug «Succinic acid forte». The experiments were carried out on chinchillas 55–61 days old. At the same time, succinic acid (Acidum succinicum) was given to the chinchillas of the experimental group for 30 days in addition to the main diet — 20 mg/kg of live weight, pre-mixed with a small amount of water, then chinchillas were fed individually from the syringe. Determination of the dynamics of live weight was carried out using individual weighing of animals at the beginning of the experiment when forming groups, and then every ten days before feeding. When analyzing the main productive indicators, a direct pattern was noted — use of succinic acid in the diet of young chinchillas led to an increase in growth rate. So, 20 days after the start of the experiment, indicators of absolute gain in live weight of experimental animals were 32.07 % (p = 0.001), and after 30 days — 45.34 % (p = < 0.001) more than in the control, where in the feeding of chinchillas, only the main diet was used without additional introduction of succinic acid.
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Fig. 1. Conditions for keeping chinchillas in the control group (a) and experimental group (б)
Source: photo by N.A. Golovacheva
Fig. 2. Scheme of experiments to study effect of succinic acid on growth indicators of chinchillas
Source: general development of the authors of the article
Fig. 3. Succinic acid
Source: photo by N.A. Golovacheva
Fig. 4. Individual feeding chinchillas with solution of succinic acid
Source: photo by N.A. Golovacheva
Fig. 5. Comparative analysis of live weight indicators of chinchillas from experimental and control groups
Source: general development of the authors of the article
Table 1. The study of live weight changes in young chinchillas during the experiment
Group | M ± SD | 95 % CI | n | p |
LW at the beginning of the experiment | ||||
Control | 127.25 ± 12.02 | 114.63–139.87 | 6 | 0.971 |
Experimental | 127.08 ± 6.41 | 120.36–133.81 | 6 | |
LW on the 10th day of the experiment | ||||
Control | 160.42 ± 12.15 | 147.67–173.16 | 6 | 0.398 |
Experimental | 166.08 ± 12.65 | 152.81–179.36 | 6 | |
LW on the 20th day of the experiment | ||||
Control | 191.17 ± 10.41 | 180.24–202.10 | 6 | 0.013* |
Experimental | 211.50 ± 14.44 | 196.35–226.65 | 6 | |
LW on the 30th day of the experiment | ||||
Control | 220.42 ± 8.61 | 211.38–229.45 | 6 | < 0.001* |
Experimental | 262.50 ± 17.56 | 244.08–280.92 | 6 | |
Note. LW — live weight of chinchillas, g; * — differences in indicators are statistically significant (p < 0.05).
Table 2. Dynamics of absolute gains in young chinchillas in experimental and control groups (n = 6)
Group | Stages of observation | p | Difference, % | |
M ± SD | 95 % CI | |||
AG on the 10th day of the experiment | ||||
Control | 33.17 ± 4.16 | 28.81–37.53 | 0.074 | ↑ 4.92 |
Experimental | 39.00 ± 7.61 | 31.01–46.99 | ||
AG on the 20th day of the experiment | ||||
Control | 63.92 ± 4.72 | 58.97–68.87 | 0.001* | ↑ 32.07 |
Experimental | 84.42 ± 8.39 | 75.62–93.22 | ||
AG on the 30th day of the experiment | ||||
Control | 93.17 ± 5.70 | 87.19–99.15 | < 0.001* | ↑ 45.34 |
Experimental | 135.42 ± 11.77 | 123.07–147.76 | ||
Note. AG — absolute gain in chinchillas, g; * — differences in indicators are statistically significant (p < 0.05).
Table 3. Average daily gains of young chinchillas in experimental and control groups
Experiment, days | Difference in average daily gains, g | Р | Increase, % | |
Control | Experiment | |||
The 10th day | 3.32 ± 0.42 | 3.90 ± 0.76 | 0.074 | ↑ 17.46 |
The 20th day | 3.08 ± 0.33 | 4.54 ± 0.61 | 0.004* | ↑ 47.40 |
The 30th day | 2.93 ± 0.22 | 5.10 ± 0.55 | < 0.001* | ↑ 74.06 |
Note. * — differences in indicators are statistically significant (p < 0.05).
Fig. 6. Dynamics of relative growth rate of chinchillas, % day‑1
Source: general development of the authors of the article
About the authors
Natalia A. Golovacheva
K.G. Razumovsky Moscow State University of Technologies and Management
Author for correspondence.
Email: n.a.golovacheva@inbox.ru
ORCID iD: 0000-0001-5832-927X
Candidate of Veterinary Sciences, Associate Professor, Department of Biology and Ichthyology
73 Zemlyanoy Val st., Moscow, 109004, Russian FederationIrina R. Selivanova
K.G. Razumovsky Moscow State University of Technologies and Management
Email: i.selivanova@mgutm.ru
ORCID iD: 0000-0002-3633-0840
Candidate of Veterinary Sciences, Associate Professor, Department of Biology and Ichthyology
73 Zemlyanoy Val st., Moscow, 109004, Russian FederationMargarita A. Chichenkova
K.G. Razumovsky Moscow State University of Technologies and Management
Email: molekula00@inbox.ru
Student, Faculty of Biotechnology and Fisheries 73 Zemlyanoy Val st., Moscow, 109004, Russian Federation
Polina A. Filatova
K.G. Razumovsky Moscow State University of Technologies and Management
Email: p._filatova@mail.ru
Student, Faculty of Biotechnology and Fisheries 73 Zemlyanoy Val st., Moscow, 109004, Russian Federation
Vera S. Antonova
K.G. Razumovsky Moscow State University of Technologies and Management
Email: v_antonoava_@mail.ru
Student, Faculty of Biotechnology and Fisheries 73 Zemlyanoy Val st., Moscow, 109004, Russian Federation
References
- Grishin VN, Moiseeva MM. Chinchilla breeding — the perspective direction of fur breeding in Russia. RUDN Journal of Agronomy and Animal Industries. 2008;4;58–69. (In Russ.).
- Spotorno AE, Zuleta CA, Valladares JP, Deane AL, Jiménez, JE. Chinchilla lanigera. Mammalian Species. 2004;2004(758):1–9. doi: 10.1644/758
- Smolentsev SY. Primenenie yantarnoi kisloty i ee proizvodnykh v zhivot-novodstve [The use of succinic acid and its derivatives in animal husbandry]. Yoshkar-Ola; 2013. (In Russ.).
- Basankin AV. Farmako-toksikologicheskoe obosnovanie primeneniya yantar-noi kisloty v zhivotnovodstve i veterinarii [Pharmaco-toxicological substantiation of the use of succinic acid in animal husbandry and veterinary science] [Dissertation]. Kazan; 2007; (In Russ.).
- Anikin AS, Perov NG, Kirilov MP. The new classification of feedstuff’s of Russia. Zootechniya. 2009;(8):12–14. (In Russ.).
- Karpukhina EG, Naidensky MS. Succinic acid is a stimulant for rabbits. Krolikovodstvo i zverovodstvo. 1997;(3):8–9. (In Russ.).
- Golovacheva NA, Nikiforov-Nikishin AL, Gorbunov AV, Kozlov AV, Tkachev AV, Tkacheva OL. Kholin’s zeolites in the system of prevention of animal salmonella infection. Veterinary medicine. 2019;(9):19–22. (In Russ.). doi: 10.30896/0042-4846.2019.22.9.19-22
- Kvartnikov MP, Kvartnikova EG, Myaldzin AR, Kiselev AL, Yakhin AY. Effect of the synthetic vitamins and microelements on the meat productivirty of the young rabbits. Krolikovodstvo i zverovodstvo. 2020;(1):14–19. (In Russ.). doi: 10.24411/0023-4885-2020-00002
- Papunidi KK, Shageev MI. Influence of the drug «Yantaros plus» on some blood parameters of piglets with rickets. In: Ecological problems of pathology, pharmacology and therapy of animals: conference proceedings. Voronezh; 1998. p.238–239. (In Russ.).
- Mordakin VN, Zakharov VA, Torzhkovф NI. Ascorbic, fumaric and citric acids in the diets of broiler chickens. Scientific heritage of professor P.A. Kostychev in the theory and practice of modern agrarian science: conference proceedings. Ryazan; 2005. p.86–90. (In Russ.).
- Mudarisov RM, Gimalova GM. The use of preparation «SOT» in feeding foxes. Krolikovodstvo i zverovodstvo. 2007;(5):7–8. (In Russ.).
- Tsyganova NA, Voronkova NA, Doronenko VD, Balabanova NF. The influence of succinic acid on the photosynthetic activity of spring soft wheat. Vestnik of Omsk SAU. 2019;(3):13–20. (In Russ.).
- Golovacheva NA, Kozlov AV, Klimov VA. Influence of amberic acid on the dynamics of the living mass of rabbits. Vestnik of Kursk state agricultural academy. 2020;(5):117–123. (In Russ.).
- Kondrashova MN. Clarified and outlined questions on the way of studying the regulation of the physiological state of succinic acid. In: Therapeutic effect of succinic acid: conference proceedings. Moscow; 1976. p.8–30. (In Russ.).
- Kanayan LR, Akopyan VI, Natishvili NN, Sahakyan SG, Aleksandryan KM, Kocharyan EN. The effect of succinic acid on embryogenesis when fed to laying hens. In: Medicinal and biologically active substances in animal husbandry and veterinary medicine. Erevan; 1986. p.54–57. (In Russ.).
- Badovskaya LA, Unzhakov AR. Prospects for the use of succinic acid in fur farming. In: Succinic acid in medicine, food industry and agriculture. Kazan-Pushchino; 1996. (In Russ.).
- Kovalenko AV, Belyakova NV. Succinic acid: pharmacological activity and dosage forms. Pharmacy. 2000;(5–6):40–43. (In Russ.).
- Basankin AV, Antipov VA. The use of succinic acid in mycotoxicoses. Veterinary pathology. 2007;(1):185–187. (In Russ.).
- Demina TM, Ratimeshina OV, Melnichenko VI. Influence of antioxidants Emicidin and Emisil on productive quality of mink. Krolikovodstvo i zverovodstvo. 2017;(3):18–21. (In Russ.).
- Golovacheva NA, Bychkova LI, Koldaeva EM, Turchakov VV. Clinical and biochemical status of rabbit blood when using succinic acid. Voprosy krolikovodstva. 2020;(5–6):52–56. (In Russ.).
- Tyutyunnik NN, Kozhevnikova LK, Meldo KI, Kondrasheva MN, Badovskaya LA, Unzhakov AR. Optimization of the physiological state and productivity of minks with succinic acid. Agricultural biology. 1999;34(4):51–56. (In Russ.).
- Blokhin GI, Blokhina TV, Selyukova EN. Amber acid and reproductive qualities of she-mink. Agrarian science. 2007;(4):21–25. (In Russ.).
- Kokorina AE. The economic effect of succinic acid addition into the diet of red foxes. In: Modern problems of nature management, hunting and fur farming: conference proceedings. Kirov; 2012. p.453–454. (In Russ.).
- Pronina NV, Sukhikh ON, Okulova II, Bespyatikh OY. Correction of oxidative stress in caged fur animals. Modern problems of nature management, hunting and fur farming: conference proceedings. Kirov; 2012. p.323–324. (In Russ.).
- Kozlov AV, Golovacheva NA, Tkachev AV, Popenko VP. New veterinary-sanitary approaches to the prevention and treatment of chinchilla coccidiosis. Actual issues in agricultural biology. 2020;(2):59–65. (In Russ.).
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