Influence of succinic acid Acidum succinicum on chinchilla growth in postembryonic period

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Abstract

In animal husbandry, special attention is paid to biological additives and natural metabolites used in the development of feeds that ensure productivity of animals and increase resistance to adverse environmental factors. Such additives actively influence energy metabolism and do not harm even in case of an overdose, due to the absence of xenobiotic effects inherent in a large number of synthetic drugs. The purpose of the research was to study growth dynamics of chinchillas against the background of drug «Succinic acid forte». The experiments were carried out on chinchillas 55–61 days old. At the same time, succinic acid (Acidum succinicum) was given to the chinchillas of the experimental group for 30 days in addition to the main diet — 20 mg/kg of live weight, pre-mixed with a small amount of water, then chinchillas were fed individually from the syringe. Determination of the dynamics of live weight was carried out using individual weighing of animals at the beginning of the experiment when forming groups, and then every ten days before feeding. When analyzing the main productive indicators, a direct pattern was noted — use of succinic acid in the diet of young chinchillas led to an increase in growth rate. So, 20 days after the start of the experiment, indicators of absolute gain in live weight of experimental animals were 32.07 % (p = 0.001), and after 30 days — 45.34 % (p = < 0.001) more than in the control, where in the feeding of chinchillas, only the main diet was used without additional introduction of succinic acid.

Full Text

 

Fig. 1. Conditions for keeping chinchillas in the control group (a) and experimental group (б)
Source: photo by N.A. Golovacheva

 

Fig. 2. Scheme of experiments to study effect of succinic acid on growth indicators of chinchillas
Source: general development of the authors of the article

 

Fig. 3. Succinic acid
Source: photo by N.A. Golovacheva

Fig. 4. Individual feeding chinchillas with solution of succinic acid
Source: photo by N.A. Golovacheva

 

Fig. 5. Comparative analysis of live weight indicators of chinchillas from experimental and control groups
Source: general development of the authors of the article

 

Table 1. The study of live weight changes in young chinchillas during the experiment

Group

M ± SD

95 % CI

n

p

LW at the beginning of the experiment

Control

127.25 ± 12.02

114.63–139.87

6

0.971

Experimental

127.08 ± 6.41

120.36–133.81

6

LW on the 10th day of the experiment

Control

160.42 ± 12.15

147.67–173.16

6

0.398

Experimental

166.08 ± 12.65

152.81–179.36

6

LW on the 20th day of the experiment

Control

191.17 ± 10.41

180.24–202.10

6

0.013*

Experimental

211.50 ± 14.44

196.35–226.65

6

LW on the 30th day of the experiment

Control

220.42 ± 8.61

211.38–229.45

6

< 0.001*

Experimental

262.50 ± 17.56

244.08–280.92

6

Note. LW — live weight of chinchillas, g; * — differences in indicators are statistically significant (p < 0.05).

 

Table 2. Dynamics of absolute gains in young chinchillas in experimental and control groups (n = 6)

Group

Stages of observation

p

Difference, %

M ± SD

95 % CI

AG on the 10th day of the experiment

Control

33.17 ± 4.16

28.81–37.53

0.074

↑ 4.92

Experimental

39.00 ± 7.61

31.01–46.99

AG on the 20th day of the experiment

Control

63.92 ± 4.72

58.97–68.87

0.001*

↑ 32.07

Experimental

84.42 ± 8.39

75.62–93.22

AG on the 30th day of the experiment

Control

93.17 ± 5.70

87.19–99.15

< 0.001*

↑ 45.34

Experimental

135.42 ± 11.77

123.07–147.76

Note. AG — absolute gain in chinchillas, g; * — differences in indicators are statistically significant (p < 0.05).

 

Table 3. Average daily gains of young chinchillas in experimental and control groups

Experiment, days

Difference in average daily gains, g

Р

Increase, %

Control

Experiment

The 10th day

3.32 ± 0.42

3.90 ± 0.76

0.074

↑ 17.46

The 20th day

3.08 ± 0.33

4.54 ± 0.61

0.004*

↑ 47.40

The 30th day

2.93 ± 0.22

5.10 ± 0.55

< 0.001*

↑ 74.06

Note. * — differences in indicators are statistically significant (p < 0.05).

 

Fig. 6. Dynamics of relative growth rate of chinchillas, % day‑1
Source: general development of the authors of the article

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About the authors

Natalia A. Golovacheva

K.G. Razumovsky Moscow State University of Technologies and Management

Author for correspondence.
Email: n.a.golovacheva@inbox.ru
ORCID iD: 0000-0001-5832-927X

Candidate of Veterinary Sciences, Associate Professor, Department of Biology and Ichthyology

73 Zemlyanoy Val st., Moscow, 109004, Russian Federation

Irina R. Selivanova

K.G. Razumovsky Moscow State University of Technologies and Management

Email: i.selivanova@mgutm.ru
ORCID iD: 0000-0002-3633-0840

Candidate of Veterinary Sciences, Associate Professor, Department of Biology and Ichthyology

73 Zemlyanoy Val st., Moscow, 109004, Russian Federation

Margarita A. Chichenkova

K.G. Razumovsky Moscow State University of Technologies and Management

Email: molekula00@inbox.ru
Student, Faculty of Biotechnology and Fisheries 73 Zemlyanoy Val st., Moscow, 109004, Russian Federation

Polina A. Filatova

K.G. Razumovsky Moscow State University of Technologies and Management

Email: p._filatova@mail.ru
Student, Faculty of Biotechnology and Fisheries 73 Zemlyanoy Val st., Moscow, 109004, Russian Federation

Vera S. Antonova

K.G. Razumovsky Moscow State University of Technologies and Management

Email: v_antonoava_@mail.ru
Student, Faculty of Biotechnology and Fisheries 73 Zemlyanoy Val st., Moscow, 109004, Russian Federation

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Supplementary files

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1. Fig. 1. Conditions for keeping chinchillas in the control group (a) and experimental group (б)

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2. Fig. 2. Scheme of experiments to study effect of succinic acid on growth indicators of chinchillas

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3. Fig. 3. Succinic acid

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4. Fig. 4. Individual feeding chinchillas with solution of succinic acid

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5. Fig. 5. Comparative analysis of live weight indicators of chinchillas from experimental and control groups

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6. Fig. 6. Dynamics of relative growth rate of chinchillas, % day‑1

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Copyright (c) 2023 Golovacheva N.A., Selivanova I.R., Chichenkova M.A., Filatova P.A., Antonova V.S.

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